Complement in Kidney Transplantation
نویسندگان
چکیده
منابع مشابه
Complement in Kidney Transplantation
The complement system is considered to be an important part of innate immune system with a significant role in inflammation processes. The activation can occur through classical, alternative, or lectin pathway, resulting in the creation of anaphylatoxins C3a and C5a, possessing a vast spectrum of immune functions, and the assembly of terminal complement cascade, capable of direct cell lysis. Th...
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Kidney transplantation in patients with end stage renal disease is preferred to dialysis because transplantation provides a better quality of life andimproved survival. However, the gap between the supply and demand for a renal allograft is widening and the waiting time is increasing. Iranian protocol, a controlled transplant program supported by the government for living unrelated donors, was ...
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The recurrence of renal disease after renal transplantation is becoming one of the main causes of graft loss after kidney transplantation. This principally concerns some of the original diseases as the atypical hemolytic uremic syndrome (HUS), the membranoproliferative glomerulonephritis (MPGN), in particular the MPGN now called C3 glomerulopathy. Both this groups of renal diseases are characte...
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Kidney Transplantation in children is the treatment of choice to treat end stage renal disease. Improvements in immunosuppressive management have dramatically reduced the risk of early acute rejection and graft loss, however the long term results in terms of graft survival and morbidity still require search for new immunosuppressive regimens. Reducing of side effects are the challenges for impr...
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In this first report on the experience with renal transplantation in children and adolescents in southern Iran during the past five years, thirty-two patients (aged 5- 19 years old 18 males, 14 females) received renal allografts. Pretransplantation pathologic diagnoses by kidney biopsy were: membranoproliferative glomerulonephritis (MPGN), rapidly progressive glomerulonephritis (RPGN), chr...
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ژورنال
عنوان ژورنال: Frontiers in Medicine
سال: 2017
ISSN: 2296-858X
DOI: 10.3389/fmed.2017.00066